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Gene Therapy and Regulation

Volume 2, No. 3, pp. 177--274, 2004

Breakthrough: designed zinc fingerproteins

Editorial --- Zincfinger nuclease-boosted gene targeting:toward clinical gene repair/alteration and custom site-specificintegrative gene therapy
R. Bertolotti 177

Engineered Cys2His2 zinc finger DNA-bindingdomains [Review article]
A.S. Hirsh and J.K.Joung 191

Emerging approach: intra-nichetransplantation

Method --- Intra-bonemarrow transplantation of hematopoieticstem cells in non-human primates:long-term engraftment without conditioning
K. Ueda,Y. Hanazono,N. Ageyama,H. Shibata,S. Ogata,Y. Ueda,T. Tabata,S. Ikehara,M. Taniwaki,M. Hasegawa,K. Teraoand K. Ozawa 207

Clinical synopsis: cancer gene therapytrials

Cancer genetherapy --- current status in theclinics [Review article]
K.J. Pulkkanen,H. Sallinen,K. Tyynela andS. Yla-Herttuala 219


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