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Gene Therapy and Regulation

Volume 1, No. 4, pp. 285--408, 2002

In Memoriam: Jeffrey M. ISNER, MD, stem cell/gene therapy pioneer
R. Bertolotti 285

Editorial --- From therapeutic angiogenesis to myocardium regeneration
R. Bertolotti 287

Therapeutic angiogenesis: pioneering clinical gene therapy trials

VEGF gene therapy for chronic critical limb ischemia
I. Baumgartner 297

Clinical trials of myocardial VEGF gene transfer
J.F. Symes, P.R. Vale, R.A. Schatz and D.W. Losordo 311

Intracoronary gene transfer of fibroblast growth factor in experimental and clinical myocardial ischemia
H.K. Hammond 325

Hepatocyte growth factor (HGF) angiogenic gene therapy: promises for cardiovascular diseases
R. Morishita, M. Aoki, N. Hashiya, K. Yamasaki, H. Makino, K. Wakayama, J. Azuma and T. Ogihara 343

Experimental cell/gene therapy: toward myocardium regeneration

Therapeutic potential of bone marrow-derived endothelial progenitor cells for cardiovascular ischemic diseases
T. Asahara, A. Kawamoto, C. Kalka and H. Masuda 361

Adult bone marrow-derived angioblasts for improvement of cardiomyocyte function after myocardial ischemia
S. Itescu, A.A. Kocher and M.D. Schuster 375

Derivation and properties of human embryonic stem cell-derived cardiomyocytes
I. Kehat and L. Gepstein 387

Spontaneous heart regeneration in adult MRL mice after cryoinjury
E. Heber-Katz, J.M. Leferovich and K. Bedelbaeva 399