Editors: Roger Bertolotti, Keiya Ozawa and H. Kirk Hammond
The first unequivocal success for Gene Therapy was reported in April 2000 for X-SCID patients. Pioneering stem cell/gene therapy clinicaltrials are the focus of this book. Therapy successes such as the X-SCIDtrial and improved ADA-SCID ones are presented together with pioneeringangio/vasculogenic clinical trials mediated either by transient genetherapy or emerging autologous stem cell transplantation. Highlightsalso include 1) promises of the breakthrough combination of stem cell-and transient gene-therapy, 2) gene therapy trials for neurodegenerativedisease on non-human primates where long-term gene therapy might involvebrain stem cells, and 3) the first clinical trial with non-invasivemonitoring of therapeutic gene expression as a prospective conclusion.
This volume will be of value and interest to researchers in thisexciting field.
2003; x+330 pages ISBN 90-6764-394-7 Price: EUR 115/US$ 155
