Editors: P.M. Frossard, H. Parvez, M. Minami, S. Parvez and H. Saito
This monograph is the fourth volume in the book seriesProgressin Hypertension. Essential hypertension is a complex, heterogeneousgroup of disorders of no definable cause. The commonly accepted viewis that genetic influences interact with environmental factors in theonset of this chronic and degenerative disease.
The aim of researchers in this field of hypertension is to unravelthe molecular and genetic architectures of the disease, in order toassess an individual=s genetic susceptibility to the disease. Themethods of molecular genetics are greatly contributing to decipherthe puzzle and much information has been gathered lately. Thepowerful combination of linkage, sib-pair and association analyses,together with studies of human genetic isolates and animal modelsallow the identification of specific genetic influences and thedevelopment of attempts at gene therapy.
The aim of this monograph is to provide a coverage of some of thesedifferent aspects of modern research in hypertension, and a summaryof what amounts to an enormous body of literature.
1999; x+266 pages ISBN 90-6764-311-4 Price (all prices are subject to change without notice): EUR 135/US$ 193
