Editors: I.N. Acworth, M. Naoi, H. Parvez and S. Parvez
This sixth volume in the book series Progress in HPLC-HPCE examines the enhancement of high-performance liquid chromatography through the development of an advanced mode of electrochemicaldetection (ECD) --- the coulometric array detection --- from its initial, yet problematic, amperometric(thin-layer) design to the highly sensitive, selective and stable coulometric (flow-through) design. Unlikeamperometric electrodes, the coulometric electrode is 100% efficient and measures signals from all of theanalyte passing through it, which leads to improved sensitivity as well as unique selectivity. Thecoulometric electrode array offers the resolution of the photodiode array with the extreme sensitivity of anelectrochemical detector.
This volume examines the use of the coulometric electrode array detector as well as its practicalapplications in neurosciences, food, environmental, pharmaceutical and agricultural sciences and those inthe are of oxidative metabolism. This collection of papers will also provide a valuable reference source toall workers in the field of HPLC and those using electrochemical detection.
1997; x+382 pages ISBN 90-6764-232-0 Price (all prices are subject to change without notice): EUR 106/US$ 152